{"id":19392,"date":"2025-12-27T09:39:09","date_gmt":"2025-12-27T09:39:09","guid":{"rendered":"https:\/\/negatius.biz\/?p=19392"},"modified":"2025-12-27T09:39:09","modified_gmt":"2025-12-27T09:39:09","slug":"scientists-analyzed-117-year-old-maria-branyass-dna-biology-and-lifestyle-including-her-mediterranean-diet-and-daily-yogurt-to-uncover-clues-to-her-e","status":"publish","type":"post","link":"https:\/\/negatius.biz\/?p=19392","title":{"rendered":"Scientists analyzed 117\u2011year\u2011old Maria\u202fBranyas\u2019s DNA, biology, and lifestyle\u2014including her Mediterranean diet and daily yogurt\u2014to uncover clues to her exceptional longevity, concluding that genetics, gut microbiome, metabolism, and lifestyle factors together likely contributed to her remarkable lifespan."},"content":{"rendered":"<p data-start=\"165\" data-end=\"946\">Maria\u202fBranyas\u202fMorera, an American\u2011born Spaniard, became one of the <strong data-start=\"232\" data-end=\"281\">longest\u2011lived people ever reliably documented<\/strong>, passing away in August\u202f2024 at <strong data-start=\"314\" data-end=\"344\">117\u202fyears and 168\u202fdays old<\/strong>. Born on March\u202f4,\u202f1907, in San\u202fFrancisco, California, she moved with her family to <strong data-start=\"428\" data-end=\"448\">Catalonia, Spain<\/strong> in 1915, where she spent most of her life and later resided in a care home in the town of Olot. Branyas held the title of <strong data-start=\"571\" data-end=\"603\">world\u2019s oldest living person<\/strong> from January\u202f2023 \u2014 after the death of French nun Lucile Randon \u2014 until her own death. She was recognized by organizations such as the <strong data-start=\"739\" data-end=\"769\">Gerontology Research Group<\/strong>, which tracks and validates supercentenarians, and was listed as one of the <strong data-start=\"846\" data-end=\"907\">few people in human history to reach such an advanced age<\/strong>.<\/p>\n<p data-start=\"948\" data-end=\"1627\">Across her extraordinary life spanning more than a century, Branyas experienced some of the defining events of modern history. She lived through <strong data-start=\"1093\" data-end=\"1215\">World War\u202fI, the Spanish Civil War, World\u202fWar\u202fII, the 1918 influenza pandemic, and more recently the COVID\u201119 pandemic<\/strong>, which she survived at age\u202f113 with only mild symptoms. Despite her age, she remained mentally engaged and communicated with the world through social media, humorously describing her X profile as \u201cI am old, very old, but not an idiot.\u201d Her longevity and demeanor earned her admiration and attention both in Spain and internationally as a symbol of resilience and longevity.<\/p>\n<p data-start=\"1629\" data-end=\"2472\">In the final years of her life, Branyas actively <strong data-start=\"1678\" data-end=\"1725\">requested that scientists study her biology<\/strong> to help uncover the secrets behind her remarkable lifespan. Researchers from the University of Barcelona, the Josep Carreras Leukemia Research Institute, and other institutions conducted one of the most <strong data-start=\"1929\" data-end=\"2004\">comprehensive scientific analyses ever undertaken on a supercentenarian<\/strong>. Known as a <strong data-start=\"2017\" data-end=\"2037\">multiomics study<\/strong>, this research examined her <strong data-start=\"2066\" data-end=\"2140\">genome, transcriptome, metabolome, proteome, microbiome, and epigenome<\/strong>, comparing her biological markers with those of younger individuals to understand why she aged so healthily. Instead of finding a simple explanation, scientists discovered a complex interplay of genetic and biological factors that helped decouple extreme age from typical age\u2011related diseases.<\/p>\n<p data-start=\"2474\" data-end=\"3327\">One of the key scientific findings was that while Branyas showed <strong data-start=\"2539\" data-end=\"2572\">some molecular signs of aging<\/strong>, she did <strong data-start=\"2582\" data-end=\"2656\">not exhibit many of the diseases commonly associated with advanced age<\/strong>, such as heart disease, cancer, or neurodegenerative disorders. Her <strong data-start=\"2725\" data-end=\"2772\">immune system appeared exceptionally robust<\/strong>, with efficient defense cells and low levels of chronic inflammation, a known driver of age\u2011related health decline. The study also highlighted <strong data-start=\"2916\" data-end=\"2941\">rare genetic variants<\/strong> in her DNA associated with longevity, effective DNA repair, and metabolic efficiency \u2014 traits that likely helped her body resist conditions that typically afflict older adults. According to researchers, this demonstrates that <strong data-start=\"3168\" data-end=\"3239\">chronological age does not necessarily equate to biological frailty<\/strong>, challenging traditional assumptions about aging.<\/p>\n<p data-start=\"3329\" data-end=\"4079\">Branyas\u2019s <strong data-start=\"3339\" data-end=\"3434\">microbiome \u2014 the community of bacteria in her gut \u2014 was another area of scientific interest<\/strong>. Researchers found that her gut bacteria profile more closely resembled that of much younger adults, which may have supported her <strong data-start=\"3565\" data-end=\"3603\">immune response and overall health<\/strong>. Diet and lifestyle also appeared to contribute: she ate a generally balanced diet consistent with Mediterranean traditions, which included fish, olive oil, and <strong data-start=\"3765\" data-end=\"3796\">daily consumption of yogurt<\/strong>, possibly influencing her gut health and inflammation levels positively. Scientists believe this combination of <strong data-start=\"3909\" data-end=\"3989\">genetic predispositions, metabolic efficiency, and beneficial gut microbiota<\/strong> helped maintain her health, even as her cells aged.<\/p>\n<p data-start=\"4081\" data-end=\"4859\">Beyond biology, Branyas herself emphasized the <strong data-start=\"4128\" data-end=\"4174\">role of lifestyle and emotional well\u2011being<\/strong> in her long life. She attributed her longevity to factors such as <strong data-start=\"4241\" data-end=\"4388\">peaceful routines, strong family connections, emotional balance, staying close to nature, positive attitude, and avoiding stress and negativity<\/strong>. These insights from her personal reflections dovetail with scientific observations that <strong data-start=\"4478\" data-end=\"4530\">psychosocial factors and supportive environments<\/strong> can play substantial roles in maintaining health into extreme old age. Her legacy continues to inspire both the scientific community and the public, offering a holistic picture of how <strong data-start=\"4715\" data-end=\"4774\">genetics, daily habits, social ties, and mental outlook<\/strong> can together shape a long and fulfilling life.<\/p>\n<p data-start=\"4861\" data-end=\"5595\">Ultimately, Maria Branyas Morera\u2019s life and the research it inspired provide <strong data-start=\"4938\" data-end=\"4980\">valuable lessons about human longevity<\/strong>. Her case shows that while genetics are undeniably important, they work in concert with lifestyle, immune function, metabolic health, and psychosocial resilience. Studies of extreme longevity like hers could inform future medical research aimed at understanding and potentially extending healthy human life. Branyas\u2019s own openness to scientific exploration \u2014 combined with her everyday life grounded in community, positivity, and simplicity \u2014 leaves a legacy that goes beyond records, offering hope and insight into what aging healthily might look like for future generations<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Maria\u202fBranyas\u202fMorera, an American\u2011born Spaniard, became one of the longest\u2011lived people ever reliably documented, passing away in August\u202f2024 at 117\u202fyears and 168\u202fdays old. Born on March\u202f4,\u202f1907, in San\u202fFrancisco,&#8230; <\/p>\n","protected":false},"author":2,"featured_media":19393,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-19392","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Scientists analyzed 117\u2011year\u2011old Maria\u202fBranyas\u2019s DNA, biology, and lifestyle\u2014including her Mediterranean diet and daily yogurt\u2014to uncover clues to her exceptional longevity, concluding that genetics, gut microbiome, metabolism, and lifestyle factors together likely contributed to her remarkable lifespan. - magazine24<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/negatius.biz\/?p=19392\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists analyzed 117\u2011year\u2011old Maria\u202fBranyas\u2019s DNA, biology, and lifestyle\u2014including her Mediterranean diet and daily yogurt\u2014to uncover clues to her exceptional longevity, concluding that genetics, gut microbiome, metabolism, and lifestyle factors together likely contributed to her remarkable lifespan. - magazine24\" \/>\n<meta property=\"og:description\" content=\"Maria\u202fBranyas\u202fMorera, an American\u2011born Spaniard, became one of the longest\u2011lived people ever reliably documented, passing away in August\u202f2024 at 117\u202fyears and 168\u202fdays old. 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