On September 15, 2025, actor Eric Dane shared an emotional message via Instagram, drawing attention for both his heartfelt delivery and visible ALS symptoms, such as slurred speech and muscle twitches. Known for roles in shows like Grey’s Anatomy, Dane used the platform to advocate for ALS awareness and research funding.

In the video, Dane wore a navy “I Am ALS” shirt and introduced himself as an actor, a father, and someone now living with ALS. He urged viewers to support the “Push for Progress” initiative, a campaign aiming to raise $1 billion within three years. The funds would go toward research, treatment access, and legislative advocacy related to ALS.

His announcement came shortly after he missed the 2025 Emmy Awards, where he was scheduled to reunite with co-star Jesse Williams in celebration of Grey’s Anatomy‘s 20th anniversary. His unexpected absence led to the cancellation of a planned tribute, which Williams delivered alone.

Dane first disclosed his ALS diagnosis in April 2025, sharing that the earliest signs were weakness in his right hand. Since then, he’s remained open about his condition, discussing both the physical and emotional impacts of the disease on his life and career.

Despite the challenges, Dane continues to act, describing his work as a vital source of focus and motivation. He referred to acting as his “lifeline,” helping him stay mentally sharp and forward-looking amid his ongoing health struggles.

He also spoke candidly about personal experiences, including a frightening boating incident where his daughter intervened, and praised his wife Rebecca Gayheart for her resilience. Through his advocacy, Dane hopes to raise awareness and inspire others, proving that determination and support can make a meaningful difference in the fight against ALS.